TB-Profiler result

Run: SRR2101621

Summary

Run ID: SRR2101621

Sample name:

Date: 03-04-2023 23:49:19

Number of reads: 564335

Percentage reads mapped: 99.36

Strain: lineage4.7

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8353 p.Gly351Ala missense_variant 1.0
mshA 576129 p.Leu261Pro missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775700 c.2781G>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417070 p.Val93Ala missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674512 p.Gly104Asp missense_variant 0.14
inhA 1674640 p.Met147Val missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155657 p.Lys152Arg missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
clpC1 4040510 p.Glu65Asp missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242865 c.-368C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 1.0
ethR 4327828 p.Pro94Ser missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407590 p.Ala205Thr missense_variant 1.0
gid 4408004 p.Asp67Tyr missense_variant 0.11
gid 4408027 c.175delC frameshift_variant 0.12