TB-Profiler result

Run: SRR21677870
Summary

Run ID: SRR21677870

Sample name:

Date: 04-04-2023 02:49:00

Number of reads: 119027

Percentage reads mapped: 93.47

Strain:

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6927 p.Leu563Ser missense_variant 0.22
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7370 p.Glu23Asp missense_variant 0.33
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9439 p.Ser713* stop_gained 0.4
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576439 c.1092G>A synonymous_variant 1.0
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoC 763539 p.Asp57Gly missense_variant 0.22
rpoC 766944 p.Arg1192Gln missense_variant 0.17
rpoC 767140 c.3771G>C synonymous_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777183 c.1297delG frameshift_variant 0.33
mmpL5 778263 p.Ile73Asn missense_variant 0.33
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304898 c.1968G>T synonymous_variant 0.67
Rv1258c 1406089 p.Ala418Ser missense_variant 1.0
Rv1258c 1406619 p.Pro241Gln missense_variant 0.5
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
atpE 1461000 c.-45C>T upstream_gene_variant 0.2
atpE 1461064 p.Ala7Val missense_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472430 n.585C>A non_coding_transcript_exon_variant 0.11
rrs 1472444 n.599A>G non_coding_transcript_exon_variant 0.12
rrs 1472493 n.649delA non_coding_transcript_exon_variant 0.15
rrl 1473451 n.-207G>A upstream_gene_variant 0.29
rrl 1473958 n.303delT non_coding_transcript_exon_variant 0.5
rrl 1474092 n.435G>T non_coding_transcript_exon_variant 0.25
rrl 1475030 n.1373G>A non_coding_transcript_exon_variant 0.29
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.4
rrl 1476087 n.2430C>T non_coding_transcript_exon_variant 0.4
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.29
rrl 1476100 n.2443A>C non_coding_transcript_exon_variant 0.29
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.29
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.29
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.29
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.29
rrl 1476116 n.2459A>G non_coding_transcript_exon_variant 0.29
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.4
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.5
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.5
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.5
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0
fabG1 1673782 p.Gly115Trp missense_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101810 c.1233C>A synonymous_variant 0.29
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2168439 p.Ser725Phe missense_variant 0.33
PPE35 2170786 c.-175delT upstream_gene_variant 0.4
Rv1979c 2221800 c.1365G>A synonymous_variant 0.4
Rv1979c 2222057 p.Asp370Asn missense_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289085 p.Asp53Tyr missense_variant 0.4
kasA 2518722 c.610delG frameshift_variant 0.5
kasA 2519104 c.990T>A synonymous_variant 0.67
eis 2715046 p.Leu96Trp missense_variant 0.4
folC 2747746 c.-149delC upstream_gene_variant 0.33
pepQ 2859524 c.894delT frameshift_variant 0.67
ribD 2987221 p.Arg128His missense_variant 0.29
Rv2752c 3065596 p.Leu199Ser missense_variant 0.5
Rv2752c 3066036 p.His52Gln missense_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087819 c.1000C>A synonymous_variant 0.29
ald 3087834 c.1016delT frameshift_variant 0.33
Rv3083 3449397 c.894C>T synonymous_variant 0.5
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474831 c.825G>T synonymous_variant 0.33
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
fbiA 3640975 p.Ala145Ser missense_variant 0.22
alr 3840739 c.682C>A synonymous_variant 0.4
rpoA 3878259 c.249G>T synonymous_variant 0.4
clpC1 4039805 c.900C>T synonymous_variant 1.0
clpC1 4039982 c.723G>A synonymous_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4243801 p.Asp190Val missense_variant 0.4
embB 4247330 p.Trp273Arg missense_variant 0.29
aftB 4267647 p.Asp397Gly missense_variant 1.0
aftB 4269693 c.-857C>T upstream_gene_variant 1.0
ethA 4326185 p.Pro430Arg missense_variant 0.15
ethA 4326676 p.Ser266Arg missense_variant 1.0
ethR 4327670 p.Pro41Gln missense_variant 1.0
ethA 4328246 c.-773C>T upstream_gene_variant 0.18
ethA 4328421 c.-948G>T upstream_gene_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407651 c.552T>C synonymous_variant 0.33
gid 4407878 p.Gly109Arg missense_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0