TB-Profiler result

Run: SRR21677880
Summary

Run ID: SRR21677880

Sample name:

Date: 04-04-2023 02:49:13

Number of reads: 109420

Percentage reads mapped: 99.15

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7089 p.Asp617Val missense_variant 0.22
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7742 c.441G>A synonymous_variant 0.33
gyrA 8015 p.Gln238His missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
ccsA 620499 c.609G>A synonymous_variant 0.29
rpoB 759881 c.75C>A synonymous_variant 0.25
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 761027 c.1221A>G synonymous_variant 0.5
rpoC 763333 c.-37G>A upstream_gene_variant 0.25
rpoC 763365 c.-4delT upstream_gene_variant 0.33
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775921 p.Leu854Met missense_variant 0.5
fbiC 1304851 p.Gly641Cys missense_variant 0.4
Rv1258c 1406745 p.Pro199Leu missense_variant 0.67
Rv1258c 1406936 c.405A>G synonymous_variant 0.4
embR 1417112 p.Leu79Pro missense_variant 0.29
atpE 1461236 c.192C>T synonymous_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472583 n.738T>G non_coding_transcript_exon_variant 0.22
rrl 1474207 n.550C>A non_coding_transcript_exon_variant 0.33
fabG1 1673462 p.Gly8Val missense_variant 0.67
inhA 1674924 c.723G>C synonymous_variant 0.5
rpsA 1833478 c.-64G>A upstream_gene_variant 1.0
rpsA 1834302 p.Val254Asp missense_variant 0.25
katG 2154868 p.Leu415Pro missense_variant 0.25
katG 2156127 c.-16T>C upstream_gene_variant 0.5
PPE35 2169382 p.Trp411Arg missense_variant 0.25
PPE35 2169758 c.855C>A synonymous_variant 0.18
Rv1979c 2221758 c.1407A>T synonymous_variant 0.29
Rv1979c 2222549 p.Ser206Pro missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
kasA 2518151 p.Ser13Gly missense_variant 0.5
eis 2714199 p.Lys378Asn missense_variant 0.4
ribD 2987006 c.170delG frameshift_variant 0.29
ribD 2987542 p.Leu235Arg missense_variant 0.25
Rv2752c 3065425 p.Gly256Val missense_variant 0.22
thyX 3067487 p.Lys153Asn missense_variant 0.67
thyA 3073692 c.780A>G synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449215 p.Trp238Arg missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474576 c.570T>C synonymous_variant 0.25
fprA 3475055 p.Gly350Asp missense_variant 0.22
fbiB 3642532 p.Arg333Leu missense_variant 0.22
rpoA 3878327 p.His61Asp missense_variant 0.4
ddn 3986779 c.-65A>G upstream_gene_variant 0.18
ddn 3986857 p.Pro5Gln missense_variant 0.18
ddn 3986874 p.Ser11Pro missense_variant 0.18
embC 4240871 p.Val337Ile missense_variant 0.4
embC 4241233 c.1371G>T synonymous_variant 0.29
embC 4241846 p.Thr662Ala missense_variant 0.67
embC 4242085 c.2223A>C synonymous_variant 0.33
embC 4242489 p.Gln876Pro missense_variant 0.5
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4248381 p.Arg623Pro missense_variant 0.25
aftB 4267665 p.Asn391Ser missense_variant 0.67
aftB 4267768 p.Leu357Met missense_variant 0.18
aftB 4267858 c.978dupG frameshift_variant 0.4
ubiA 4269161 p.Ser225Pro missense_variant 0.29
ethA 4326457 p.Ile339Met missense_variant 0.29
ethA 4327262 p.Gly71Val missense_variant 0.5
ethA 4327782 c.-309C>G upstream_gene_variant 0.18