TB-Profiler result

Run: SRR21677882

Summary

Run ID: SRR21677882

Sample name:

Date: 04-04-2023 02:49:28

Number of reads: 571638

Percentage reads mapped: 99.81

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9503 c.2202T>C synonymous_variant 0.17
rplC 801219 c.411C>T synonymous_variant 0.11
fbiC 1304917 p.Thr663Ser missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.13
rpsA 1833413 c.-129G>T upstream_gene_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167846 p.Ser923Cys missense_variant 0.14
PPE35 2170602 p.Ser4* stop_gained 0.11
Rv1979c 2222322 p.Lys281Asn missense_variant 0.11
kasA 2518697 p.Cys195Arg missense_variant 0.12
kasA 2519128 c.1014G>C synonymous_variant 0.21
kasA 2519131 c.1017G>C synonymous_variant 0.21
kasA 2519140 c.1026G>C synonymous_variant 0.13
kasA 2519143 c.1029G>C synonymous_variant 0.13
pepQ 2859407 c.1011delC frameshift_variant 0.1
Rv3083 3449552 p.Ile350Thr missense_variant 0.11
Rv3236c 3613292 c.-177delG upstream_gene_variant 0.12
clpC1 4040321 c.384C>T synonymous_variant 0.1
embA 4242580 c.-653G>A upstream_gene_variant 0.17
embA 4245708 p.Ala826Ser missense_variant 0.13
embB 4249668 p.Tyr1052Cys missense_variant 0.12
ubiA 4269947 c.-114G>T upstream_gene_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0