TB-Profiler result

Run: SRR21764251
Summary

Run ID: SRR21764251

Sample name:

Date: 04-04-2023 03:33:57

Number of reads: 28971914

Percentage reads mapped: 93.95

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761140 p.His445Pro missense_variant 0.36 rifampicin
rpoB 761155 p.Ser450Leu missense_variant 0.46 rifampicin
rrs 1473246 n.1401A>G non_coding_transcript_exon_variant 0.96 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
PPE35 2170598 c.15G>A synonymous_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.3