TB-Profiler result

Run: SRR22048372
Summary

Run ID: SRR22048372

Sample name:

Date: 04-04-2023 03:44:36

Number of reads: 1149380

Percentage reads mapped: 97.04

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575891 p.Ala182Thr missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.31
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471978 n.133C>T non_coding_transcript_exon_variant 0.12
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169147 p.Ala489Val missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223332 c.-168A>C upstream_gene_variant 0.16
fbiD 3339593 p.His159Pro missense_variant 0.11
rpoA 3878491 p.Arg6His missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242928 c.-305A>G upstream_gene_variant 1.0
embB 4247595 p.Cys361Ser missense_variant 1.0
embB 4247810 p.Leu433Met missense_variant 0.18
aftB 4267883 c.954C>T synonymous_variant 0.12
aftB 4268040 p.Leu266Pro missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0