TB-Profiler result

Run: SRR22196583
Summary

Run ID: SRR22196583

Sample name:

Date: 04-04-2023 04:06:05

Number of reads: 114030

Percentage reads mapped: 96.85

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9099 p.Leu600Ile missense_variant 0.29
fgd1 491493 c.711C>A synonymous_variant 0.22
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
ccsA 620319 c.429C>A synonymous_variant 0.33
rpoB 760107 p.Phe101Val missense_variant 0.67
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 764190 p.Ala274Asp missense_variant 0.5
rpoC 764432 p.Lys355* stop_gained 0.4
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801169 p.Lys121Gln missense_variant 0.67
embR 1416373 c.975C>A synonymous_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474034 n.377G>T non_coding_transcript_exon_variant 0.5
rrl 1474939 n.1282C>A non_coding_transcript_exon_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169850 p.Asn255Asp missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726499 p.Leu103Ile missense_variant 0.33
Rv2752c 3064820 p.Gly458Ser missense_variant 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087006 p.Gln63* stop_gained 0.2
fbiD 3339609 c.492G>T synonymous_variant 0.29
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474496 p.Arg164Trp missense_variant 0.4
fprA 3474774 c.768G>T synonymous_variant 0.5
whiB7 3568688 c.-9A>G upstream_gene_variant 0.4
Rv3236c 3612534 p.Ala195Ser missense_variant 0.67
Rv3236c 3612655 c.462G>C synonymous_variant 0.5
fbiA 3641332 p.Gly264Arg missense_variant 0.33
clpC1 4038218 p.Glu829Asp missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embC 4242996 p.Val1045Glu missense_variant 0.4
embA 4243725 p.Glu165* stop_gained 0.29
embB 4247476 c.963C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0