TB-Profiler result

Run: SRR23055174
Summary

Run ID: SRR23055174

Sample name:

Date: 13-03-2023 18:33:25

Number of reads: 3959049

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576100 p.Asp251Glu missense_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
pepQ 2860153 p.Glu89Ala missense_variant 0.15
fbiD 3339719 p.Leu201Arg missense_variant 0.25
fbiD 3339726 c.609A>C synonymous_variant 0.15
rpoA 3878569 c.-67delG upstream_gene_variant 0.13
panD 4043882 p.Pro134Ala missense_variant 1.0
embB 4247028 p.Leu172Arg missense_variant 0.21
panD 4043882 c.-899_399del start_lost&conservative_inframe_deletion 1.0