TB-Profiler result

Run: SRR23071817

Summary

Run ID: SRR23071817

Sample name:

Date: 13-03-2023 18:43:57

Number of reads: 6591033

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: HR-TB


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155966 c.145_146insT frameshift_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576100 p.Asp251Glu missense_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
whiB7 3568437 c.243T>G synonymous_variant 0.16
rpoA 3878649 c.-146A>C upstream_gene_variant 0.14
embB 4248309 p.Phe599Cys missense_variant 0.16
embB 4248319 c.1806A>C synonymous_variant 0.15
panD 4043882 c.-899_399del start_lost&conservative_inframe_deletion 1.0