TB-Profiler result

Run: SRR23082537

Summary

Run ID: SRR23082537

Sample name:

Date: 13-03-2023 19:00:37

Number of reads: 5039825

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576100 p.Asp251Glu missense_variant 0.16
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
pepQ 2860153 p.Glu89Ala missense_variant 0.13
fbiD 3339720 c.603C>G synonymous_variant 0.16
whiB7 3568428 c.252A>C synonymous_variant 0.15
whiB7 3568437 c.243T>G synonymous_variant 0.16
rpoA 3878609 c.-102T>G upstream_gene_variant 0.2
rpoA 3878618 c.-111A>C upstream_gene_variant 0.14
rpoA 3878649 c.-142T>G upstream_gene_variant 0.15
rpoA 3878653 c.-146A>C upstream_gene_variant 0.12
panD 4043882 c.-899_399del start_lost&conservative_inframe_deletion 1.0