TB-Profiler result

Run: SRR23082543

Summary

Run ID: SRR23082543

Sample name:

Date: 13-03-2023 19:12:46

Number of reads: 4853893

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576100 p.Asp251Glu missense_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
kasA 2519079 p.Glu322Ala missense_variant 0.15
Rv2752c 3064834 p.Ile453Ser missense_variant 0.22
Rv2752c 3064849 p.Phe448Cys missense_variant 0.15
fbiD 3339719 p.Leu201Arg missense_variant 0.22
fbiD 3339747 p.Val211Gly missense_variant 0.17
whiB7 3568428 c.252A>C synonymous_variant 0.29
rpoA 3878630 c.-146A>C upstream_gene_variant 0.19
panD 4043882 p.Pro134Ala missense_variant 1.0
embB 4247015 p.Ser168Ala missense_variant 0.2
embB 4247028 p.Leu172Arg missense_variant 0.2
embB 4248309 p.Phe599Cys missense_variant 0.15
embB 4248319 c.1806A>C synonymous_variant 0.15
aftB 4268619 p.Val73Gly missense_variant 0.15
whiB6 4338205 p.Val106Gly missense_variant 0.17
panD 4043882 c.-899_399del start_lost&conservative_inframe_deletion 1.0