TB-Profiler result

Run: SRR23082545

Summary

Run ID: SRR23082545

Sample name:

Date: 04-04-2023 04:21:38

Number of reads: 5255310

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576100 p.Asp251Glu missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
kasA 2519079 p.Glu322Ala missense_variant 0.22
kasA 2519097 p.Val328Gly missense_variant 0.13
whiB7 3568437 c.243T>G synonymous_variant 0.15
rpoA 3878613 c.-106A>C upstream_gene_variant 0.12
embB 4247028 p.Leu172Arg missense_variant 0.13
embB 4247039 p.Phe176Val missense_variant 0.11
embB 4248309 p.Phe599Cys missense_variant 0.19
embB 4248319 c.1806A>C synonymous_variant 0.14
panD 4043882 c.-899_399del start_lost&conservative_inframe_deletion 1.0