TB-Profiler result

Run: SRR23082910

Summary

Run ID: SRR23082910

Sample name:

Date: 18-03-2023 19:26:48

Number of reads: 7412423

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Other


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
eis 2715346 c.-14C>T upstream_gene_variant 0.17 kanamycin, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
kasA 2519079 p.Glu322Ala missense_variant 0.13
kasA 2519104 c.990T>G synonymous_variant 0.18
rpoA 3878608 c.-101C>G upstream_gene_variant 0.14
rpoA 3878609 c.-102T>G upstream_gene_variant 0.14
embB 4248319 c.1806A>C synonymous_variant 0.12
panD 4043882 c.-897_399del start_lost&conservative_inframe_deletion 1.0