TB-Profiler result

Run: SRR29096294
Summary

Run ID: SRR29096294

Sample name:

Date: 2025-07-28T05:08:44.148220

Number of reads: 177692

Percentage reads mapped: 99.45

Median coverage: 5.0

Strain: lineage4.6.1.2

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 100.0
lineage4.6 Euro-American None 100.0
lineage4.6.1 Euro-American (Uganda) RD724 100.0
lineage4.6.1.2 Euro-American RD724 100.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
whiB7 3569029 c.-350A>G upstream_gene_variant 1.0 amikacin Uncertain significance
kanamycin Not assoc w R
streptomycin Uncertain significance
embA 4243709 c.477C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim