TB-Profiler result

Run: SRR3675233
Summary

Run ID: SRR3675233

Sample name:

Date: 04-04-2023 05:23:04

Number of reads: 268673

Percentage reads mapped: 88.47

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 620270 p.Val127Ala missense_variant 0.15
mmpL5 775596 p.Ala962Val missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417223 p.Leu42Ser missense_variant 0.14
rpsA 1834809 p.Arg423His missense_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102055 p.Pro330Ser missense_variant 1.0
PPE35 2168076 p.Thr846Met missense_variant 1.0
PPE35 2168087 c.2525delC frameshift_variant 0.5
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726341 p.Val50Gly missense_variant 0.67
fbiB 3642454 p.Ala307Val missense_variant 0.33
alr 3841256 c.165C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338254 p.Phe90Leu missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0