TB-Profiler result

Run: SRR4034306
Summary

Run ID: SRR4034306

Sample name:

Date: 04-04-2023 06:42:20

Number of reads: 372315

Percentage reads mapped: 99.52

Strain: lineage4.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8061 p.Arg254Cys missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 760606 c.801delG frameshift_variant 0.33
rpoC 764263 c.894G>A synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766264 c.2895G>A synonymous_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777320 c.1161C>G synonymous_variant 1.0
mmpR5 779371 p.Ala128Pro missense_variant 0.4
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302762 c.-169C>A upstream_gene_variant 0.13
fbiC 1303289 p.Ser120Thr missense_variant 0.18
fbiC 1305298 p.Lys790* stop_gained 0.15
Rv1258c 1406592 p.Tyr250Cys missense_variant 0.17
embR 1417476 c.-129A>G upstream_gene_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474652 n.996delA non_coding_transcript_exon_variant 0.5
rrl 1476473 n.2816G>A non_coding_transcript_exon_variant 0.67
inhA 1674825 c.624C>A synonymous_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2221990 p.Ala392Asp missense_variant 0.33
Rv1979c 2223252 c.-88G>A upstream_gene_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
eis 2714775 c.558G>T synonymous_variant 0.13
eis 2714896 p.Phe146Ser missense_variant 0.2
eis 2715132 c.201G>A synonymous_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3611974 c.1143A>C synonymous_variant 1.0
fbiA 3640718 p.Cys59Tyr missense_variant 0.13
fbiB 3641881 p.Ser116Tyr missense_variant 0.5
embA 4242322 c.-911C>A upstream_gene_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4245203 c.1971C>A synonymous_variant 0.33
embA 4246351 p.Ser1040* stop_gained 0.29
embB 4248700 p.Gln729His missense_variant 0.22
aftB 4267329 p.Arg503Leu missense_variant 0.22
ethA 4328227 c.-755delT upstream_gene_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0