TB-Profiler result

Run: SRR4034482
Summary

Run ID: SRR4034482

Sample name:

Date: 04-04-2023 06:49:58

Number of reads: 192123

Percentage reads mapped: 99.74

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5283 p.Ala15Val missense_variant 0.67
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8930 c.1629C>T synonymous_variant 0.33
gyrA 9295 c.1996delT frameshift_variant 0.33
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 779022 c.-542G>A upstream_gene_variant 0.25
Rv1258c 1407464 c.-124G>A upstream_gene_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
rrl 1475229 n.1574dupC non_coding_transcript_exon_variant 0.4
rrl 1476348 n.2691A>T non_coding_transcript_exon_variant 0.22
rpsA 1833584 p.Asp15Asn missense_variant 0.33
tlyA 1918593 c.654G>T synonymous_variant 0.5
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518280 c.167delT frameshift_variant 0.29
Rv2752c 3066356 c.-169_-166dupTGGG upstream_gene_variant 0.33
thyX 3067940 c.6C>A synonymous_variant 0.5
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087620 c.801A>C synonymous_variant 0.33
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642154 p.Gly207Asp missense_variant 0.5
fbiB 3642672 p.Ala380Thr missense_variant 0.29
panD 4043874 c.408C>T synonymous_variant 0.4
aftB 4267417 p.Pro474Ser missense_variant 0.29
ethR 4327858 p.Arg104Cys missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0