TB-Profiler result

Run: SRR4034537
Summary

Run ID: SRR4034537

Sample name:

Date: 04-04-2023 06:52:09

Number of reads: 148316

Percentage reads mapped: 99.83

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.88
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 761020 p.Ala405Glu missense_variant 0.67
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrl 1474721 n.1064G>T non_coding_transcript_exon_variant 0.67
katG 2154129 c.1983G>A synonymous_variant 0.67
PPE35 2170408 p.Ala69Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065924 p.Ile90Val missense_variant 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473872 c.-135G>A upstream_gene_variant 0.33
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245712 p.Ala827Val missense_variant 0.33
embB 4247988 p.Val492Ala missense_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0