TB-Profiler result

Run: SRR4034539

Summary

Run ID: SRR4034539

Sample name:

Date: 04-04-2023 06:52:15

Number of reads: 152788

Percentage reads mapped: 99.72

Strain: lineage4.3.2

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.12
lineage4.3.2 Euro-American (LAM) LAM3 None 0.13
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7689 p.Thr130Ala missense_variant 0.5
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
rpsA 1833352 c.-190C>A upstream_gene_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168787 c.1825delA frameshift_variant 0.22
PPE35 2168821 p.Ala598Thr missense_variant 0.2
kasA 2518951 c.840delC frameshift_variant 1.0
ahpC 2726458 p.Ser89Asn missense_variant 0.29
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242972 p.Glu1037Gly missense_variant 0.25
embB 4247288 p.Ala259Thr missense_variant 0.4
aftB 4268031 c.804_805dupGC frameshift_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0