TB-Profiler result

Run: SRR4034540

Summary

Run ID: SRR4034540

Sample name:

Date: 04-04-2023 06:52:17

Number of reads: 187856

Percentage reads mapped: 99.78

Strain: lineage4

Drug-resistance: Other


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
ethA 4326486 c.987delA frameshift_variant 0.5 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5967 p.Pro243Leu missense_variant 0.4
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620285 p.Ala132Val missense_variant 0.22
rpoB 760763 c.957C>A synonymous_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775688 c.2793C>A synonymous_variant 0.29
mmpL5 775787 c.2694C>T synonymous_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474870 c.864G>T synonymous_variant 1.0
Rv3236c 3612560 p.Thr186Met missense_variant 0.4
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244797 p.Leu522Pro missense_variant 0.67
embB 4247037 p.Gly175Asp missense_variant 0.4
gid 4408156 p.Leu16Arg missense_variant 1.0