TB-Profiler result

Run: SRR4037758
Summary

Run ID: SRR4037758

Sample name:

Date: 04-04-2023 07:38:28

Number of reads: 344917

Percentage reads mapped: 99.68

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5678 p.Ser147Ala missense_variant 0.29
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7874 c.573G>A synonymous_variant 0.25
gyrA 9138 p.Gln613Glu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491706 c.924G>T synonymous_variant 0.33
ccsA 619741 c.-150G>A upstream_gene_variant 0.67
ccsA 620625 p.Ile245Met missense_variant 0.4
rpoB 759855 p.Arg17Ser missense_variant 0.22
rpoB 762663 p.Leu953Met missense_variant 0.29
rpoC 763584 p.Gly72Asp missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 0.19
mmpL5 776232 p.Pro750Gln missense_variant 0.17
mmpL5 776850 p.Gln544Arg missense_variant 0.29
mmpL5 776964 p.Thr506Ile missense_variant 0.15
mmpL5 777416 c.1065G>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303151 p.Gly74Asp missense_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475268 n.1613_1615delGAG non_coding_transcript_exon_variant 0.25
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.2
rrl 1476730 n.3073G>T non_coding_transcript_exon_variant 0.15
inhA 1673363 c.-839G>A upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168479 p.Thr712Pro missense_variant 1.0
PPE35 2168516 c.2097C>A synonymous_variant 0.5
PPE35 2169320 p.Leu431Phe missense_variant 0.5
PPE35 2169595 p.Gly340Cys missense_variant 0.18
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289367 c.-127delG upstream_gene_variant 0.25
folC 2746660 c.938delT frameshift_variant 0.67
folC 2747296 c.303G>A synonymous_variant 0.29
pepQ 2860313 p.Phe36Leu missense_variant 0.29
Rv2752c 3066175 p.Pro6Arg missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568779 c.-100T>C upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 0.75
Rv3236c 3612813 p.Thr102Ala missense_variant 0.4
fbiB 3642547 p.Gly338Val missense_variant 0.4
clpC1 4039314 p.Arg464His missense_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0