TB-Profiler result

Run: SRR5013502
Summary

Run ID: SRR5013502

Sample name:

Date: 2024-04-16T06:07:23.067407

Number of reads: 3714944

Percentage reads mapped: 56.46

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
ndh 2102730 p.Gly105Ser missense_variant 0.91 ethionamide
delamanid
isoniazid
pncA 2288682 c.560G>A splice_region_variant&stop_retained_variant 0.99 pyrazinamide Not assoc w R - Interim
pncA 2289242 c.-1T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289245 c.-4A>C upstream_gene_variant 1.0 pyrazinamide
mtrB 3626636 c.-23A>G upstream_gene_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrA 3627038 p.Met104Ile missense_variant 1.0 bedaquiline
rifampicin Uncertain significance