TB-Profiler result

Run: SRR5485405
Summary

Run ID: SRR5485405

Sample name:

Date: 18-08-2022 08:28:23

Number of reads: 92812

Percentage reads mapped: 98.89

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 1.0 streptomycin
pncA 2289223 p.Val7Ile missense_variant 0.17 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpsL 781661 p.Cys34Trp missense_variant 0.19
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.32
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289052 p.Tyr64His missense_variant 0.17