TB-Profiler result

Run: SRR5485409
Summary

Run ID: SRR5485409

Sample name:

Date: 18-08-2022 08:28:04

Number of reads: 102449

Percentage reads mapped: 92.57

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
embB 4247448 p.His312Arg missense_variant 0.14 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761075 c.1269G>A synonymous_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.3
rrs 1472652 n.807A>C non_coding_transcript_exon_variant 0.18
rrs 1473239 n.1394G>A non_coding_transcript_exon_variant 0.2
rrs 1473291 n.1446G>A non_coding_transcript_exon_variant 0.18
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289151 p.Ile31Leu missense_variant 0.17
embB 4247351 c.839delA frameshift_variant 0.15