TB-Profiler result

Run: SRR5485413
Summary

Run ID: SRR5485413

Sample name:

Date: 18-08-2022 08:27:42

Number of reads: 122190

Percentage reads mapped: 94.53

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247399 p.Asn296His missense_variant 0.18 ethambutol
embB 4247465 p.Asn318His missense_variant 0.15 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.23
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.26
embB 4247352 p.Asp280Ala missense_variant 0.2
embB 4247448 p.His312Pro missense_variant 0.18