TB-Profiler result

Run: SRR5485415
Summary

Run ID: SRR5485415

Sample name:

Date: 18-08-2022 08:27:41

Number of reads: 66109

Percentage reads mapped: 61.35

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.15 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6634 c.-668T>C upstream_gene_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.33
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.15
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 0.15
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.15
fabG1 1673422 c.-18A>G upstream_gene_variant 0.18
pncA 2289047 c.195C>T synonymous_variant 1.0
embB 4247596 p.Cys361* stop_gained 0.15