TB-Profiler result

Run: SRR5485416
Summary

Run ID: SRR5485416

Sample name:

Date: 18-08-2022 08:27:19

Number of reads: 126498

Percentage reads mapped: 97.65

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 0.94 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6504 p.Lys422Thr missense_variant 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.29
rrs 1472708 n.863T>C non_coding_transcript_exon_variant 0.17
rrs 1473356 n.1511A>G non_coding_transcript_exon_variant 0.19
fabG1 1673368 c.-72A>G upstream_gene_variant 0.18
pncA 2289047 c.195C>T synonymous_variant 1.0
embB 4247352 p.Asp280Ala missense_variant 0.15