TB-Profiler result

Run: SRR5485417
Summary

Run ID: SRR5485417

Sample name:

Date: 18-08-2022 08:27:19

Number of reads: 119063

Percentage reads mapped: 95.56

Strain:

Drug-resistance: MDR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761110 p.Asp435Val missense_variant 1.0 rifampicin
katG 2155167 p.Ser315Thr missense_variant 0.15 isoniazid
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761228 p.Tyr474* stop_gained 0.23
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.26
katG 2155098 c.1014C>A synonymous_variant 0.17
pncA 2289255 c.-14C>T upstream_gene_variant 0.2