TB-Profiler result

Run: SRR5485459

Summary

Run ID: SRR5485459

Sample name:

Date: 18-08-2022 08:30:46

Number of reads: 114889

Percentage reads mapped: 92.24

Strain:

Drug-resistance: MDR-TB


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247431 p.Met306Ile missense_variant 0.9 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6629 p.Gly464Ser missense_variant 0.27
rrs 1472301 n.456C>G non_coding_transcript_exon_variant 0.15
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.36
rrs 1472720 n.875C>T non_coding_transcript_exon_variant 0.18
pncA 2289138 p.Leu35Arg missense_variant 0.2