TB-Profiler result

Run: SRR5485461
Summary

Run ID: SRR5485461

Sample name:

Date: 18-08-2022 08:30:27

Number of reads: 153657

Percentage reads mapped: 95.24

Strain:

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155130 p.Trp328Gly missense_variant 0.15 isoniazid
katG 2155167 p.Ser315Thr missense_variant 0.15 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472301 n.456C>G non_coding_transcript_exon_variant 0.17
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.19
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.27
katG 2155097 p.Tyr339Asp missense_variant 0.15
katG 2155098 c.1014C>A synonymous_variant 0.15
katG 2155115 p.Leu333Ile missense_variant 0.14
pncA 2289151 p.Ile31Leu missense_variant 0.16
pncA 2289256 c.-15A>G upstream_gene_variant 0.13
embB 4247716 c.1203C>T synonymous_variant 0.14