TB-Profiler result

Run: SRR5485472
Summary

Run ID: SRR5485472

Sample name:

Date: 18-08-2022 08:29:47

Number of reads: 121126

Percentage reads mapped: 98.61

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761139 p.His445Asp missense_variant 1.0 rifampicin
pncA 2289114 p.His43Pro missense_variant 0.2 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.24
rrs 1473234 n.1389A>G non_coding_transcript_exon_variant 0.18
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.18
rrl 1473509 n.-148delC upstream_gene_variant 0.18
eis 2715278 c.55C>T synonymous_variant 0.15
embB 4247699 p.Met396Leu missense_variant 0.18
embB 4247702 p.Pro397Ser missense_variant 0.18