TB-Profiler result

Run: SRR5485473
Summary

Run ID: SRR5485473

Sample name:

Date: 18-08-2022 08:29:47

Number of reads: 109315

Percentage reads mapped: 96.11

Strain:

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
katG 2155130 p.Trp328Gly missense_variant 0.15 isoniazid
katG 2155167 p.Ser315Arg missense_variant 0.15 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.29
katG 2155097 p.Tyr339Asp missense_variant 0.31
katG 2155098 c.1014C>A synonymous_variant 0.15
katG 2155174 p.Ile313Ser missense_variant 0.15
pncA 2289052 p.Tyr64His missense_variant 0.13
pncA 2289151 p.Ile31Leu missense_variant 0.22
pncA 2289194 c.48T>A synonymous_variant 0.14
eis 2715263 p.Phe24Leu missense_variant 0.18