TB-Profiler result

Run: SRR5485474
Summary

Run ID: SRR5485474

Sample name:

Date: 18-08-2022 08:29:47

Number of reads: 112466

Percentage reads mapped: 95.21

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
embB 4247429 p.Met306Val missense_variant 0.93 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.15
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.21
rrs 1473285 n.1440A>G non_coding_transcript_exon_variant 0.2
pncA 2289151 p.Ile31Leu missense_variant 0.23
eis 2715269 p.Ala22Thr missense_variant 0.2
embB 4247710 c.1197C>T synonymous_variant 0.17