TB-Profiler result

Run: SRR5485503
Summary

Run ID: SRR5485503

Sample name:

Date: 18-08-2022 08:36:03

Number of reads: 126809

Percentage reads mapped: 97.04

Strain:

Drug-resistance: MDR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
fabG1 1673423 c.-17G>T upstream_gene_variant 1.0 isoniazid, ethionamide
pncA 2288835 p.Asp136Gly missense_variant 0.17 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6645 p.Ser469Asn missense_variant 0.13
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.54
rrs 1472506 n.661A>C non_coding_transcript_exon_variant 0.17
rrs 1472540 n.695A>G non_coding_transcript_exon_variant 0.17
rrs 1472679 n.834T>C non_coding_transcript_exon_variant 0.17
fabG1 1673377 c.-63C>T upstream_gene_variant 0.17
embB 4247475 p.Arg321His missense_variant 0.19