TB-Profiler result

Run: SRR5485505
Summary

Run ID: SRR5485505

Sample name:

Date: 18-08-2022 08:36:05

Number of reads: 305860

Percentage reads mapped: 99.6

Strain:

Drug-resistance: MDR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761161 p.Leu452Pro missense_variant 1.0 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247729 p.Gly406Ser missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6501 p.Arg421Pro missense_variant 0.2
gyrA 7529 c.228G>C synonymous_variant 0.17
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7732 p.Glu144Gly missense_variant 0.17
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.22
fabG1 1673485 p.Arg16Ser missense_variant 0.25
embB 4247796 p.Leu428Arg missense_variant 0.18