TB-Profiler result

Run: SRR5485518
Summary

Run ID: SRR5485518

Sample name:

Date: 2024-04-15T15:14:21.343824

Number of reads: 249723

Percentage reads mapped: 99.08

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: RR-TB

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB p.Gln432Leu Assoc w R
p.Ser450Leu Assoc w R
isoniazid
ethambutol
pyrazinamide
streptomycin rrs n.514A>C Assoc w R
n.517C>T Assoc w R
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rpoB 761101 p.Gln432Leu missense_variant 0.5 rifampicin Assoc w R
rpoB 761155 p.Ser450Leu missense_variant 0.52 rifampicin Assoc w R
rrs 1472359 n.514A>C non_coding_transcript_exon_variant 0.32 streptomycin Assoc w R
rrs 1472362 n.517C>T non_coding_transcript_exon_variant 0.65 streptomycin Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence