TB-Profiler result

Run: SRR5485520
Summary

Run ID: SRR5485520

Sample name:

Date: 18-08-2022 08:33:25

Number of reads: 203311

Percentage reads mapped: 99.36

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761101 p.Gln432Leu missense_variant 1.0 rifampicin
rrs 1472359 n.514A>C non_coding_transcript_exon_variant 1.0 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
pncA 2289248 c.-7T>C upstream_gene_variant 0.27 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.38
fabG1 1673485 p.Arg16Ser missense_variant 0.2
pncA 2289264 c.-23T>C upstream_gene_variant 0.2
embB 4247717 p.Leu402Met missense_variant 0.17