TB-Profiler result

Run: SRR5485524
Summary

Run ID: SRR5485524

Sample name:

Date: 18-08-2022 08:32:54

Number of reads: 244531

Percentage reads mapped: 99.28

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7654 p.Ser118Leu missense_variant 0.15
rpoB 761141 c.1335C>T synonymous_variant 0.16
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.28
pncA 2288844 p.Ile133Ser missense_variant 1.0