TB-Profiler result

Run: SRR5485549
Summary

Run ID: SRR5485549

Sample name:

Date: 18-08-2022 08:27:01

Number of reads: 110188

Percentage reads mapped: 99.1

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
embB 4247429 p.Met306Leu missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7671 p.Pro124Ser missense_variant 0.17
rpoB 761228 p.Tyr474* stop_gained 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.3
rrs 1473269 n.1424C>G non_coding_transcript_exon_variant 0.2
embB 4247596 p.Cys361* stop_gained 0.14
embB 4247612 p.Arg367Gly missense_variant 0.15