TB-Profiler result

Run: SRR5485555
Summary

Run ID: SRR5485555

Sample name:

Date: 18-08-2022 08:26:39

Number of reads: 122263

Percentage reads mapped: 99.36

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761110 p.Asp435Val missense_variant 1.0 rifampicin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6746 p.Gln503Lys missense_variant 0.2
gyrB 6753 p.Ile505Ser missense_variant 0.2
gyrA 6757 c.-545C>A upstream_gene_variant 0.2
gyrA 7628 c.327G>A synonymous_variant 0.2
rpoB 761228 p.Tyr474* stop_gained 0.15
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.27
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.24
katG 2155091 p.Trp341Gly missense_variant 0.17
pncA 2289047 c.195C>T synonymous_variant 1.0
eis 2715275 p.Ala20Thr missense_variant 0.14