TB-Profiler result

Run: SRR5485557
Summary

Run ID: SRR5485557

Sample name:

Date: 18-08-2022 08:26:20

Number of reads: 112987

Percentage reads mapped: 99.28

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rrs 1472362 n.517C>T non_coding_transcript_exon_variant 0.97 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247431 p.Met306Ile missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6650 p.Arg471Cys missense_variant 0.14
gyrA 7642 p.Gly114Asp missense_variant 0.17
rpoB 761059 p.Val418Gly missense_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.3
eis 2715252 c.80delT frameshift_variant 0.15