TB-Profiler result

Run: SRR5485564
Summary

Run ID: SRR5485564

Sample name:

Date: 18-08-2022 08:25:55

Number of reads: 134350

Percentage reads mapped: 99.25

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
embB 4247574 p.Asp354Ala missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6633 p.Gly465Asp missense_variant 0.14
rpsL 781661 p.Cys34Trp missense_variant 0.29
rrs 1472301 n.456C>G non_coding_transcript_exon_variant 0.15
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.14
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.19
fabG1 1673378 c.-62C>T upstream_gene_variant 0.17