TB-Profiler result

Run: SRR5485577
Summary

Run ID: SRR5485577

Sample name:

Date: 18-08-2022 08:24:54

Number of reads: 114173

Percentage reads mapped: 97.48

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 0.91 streptomycin
embB 4247429 p.Met306Val missense_variant 0.94 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6633 p.Gly465Asp missense_variant 0.13
rpoB 761228 p.Tyr474* stop_gained 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.28
rrs 1472724 n.879G>A non_coding_transcript_exon_variant 0.13
rrs 1473289 n.1444T>C non_coding_transcript_exon_variant 0.2
pncA 2288924 p.Phe106Leu missense_variant 0.2