TB-Profiler result

Run: SRR5485580
Summary

Run ID: SRR5485580

Sample name:

Date: 18-08-2022 08:24:41

Number of reads: 122173

Percentage reads mapped: 99.11

Strain:

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
katG 2155187 p.Gly309Ser missense_variant 0.17 isoniazid
embB 4247431 p.Met306Ile missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761218 p.Pro471Gln missense_variant 0.18
rpsL 781816 p.Arg86Gln missense_variant 0.17
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.28
fabG1 1673398 c.-42A>C upstream_gene_variant 0.18
pncA 2288924 p.Phe106Val missense_variant 0.17
eis 2715171 c.162G>A synonymous_variant 0.15