TB-Profiler result

Run: SRR5485585
Summary

Run ID: SRR5485585

Sample name:

Date: 18-08-2022 08:24:12

Number of reads: 104352

Percentage reads mapped: 99.27

Strain:

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2288973 p.Ile90Ser missense_variant 0.17 pyrazinamide
pncA 2289081 p.Pro54Leu missense_variant 1.0 pyrazinamide
pncA 2289114 p.His43Pro missense_variant 0.15 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6503 p.Lys422Gln missense_variant 0.2
gyrB 6540 p.Asp434Ala missense_variant 0.2
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.32
rrs 1473207 n.1364delG non_coding_transcript_exon_variant 0.22
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.17
pncA 2289100 p.Lys48Gln missense_variant 0.17