TB-Profiler result

Run: SRR5485587
Summary

Run ID: SRR5485587

Sample name:

Date: 18-08-2022 08:23:59

Number of reads: 97291

Percentage reads mapped: 98.95

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
pncA 2288821 p.Gln141* stop_gained 0.17 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472301 n.456C>G non_coding_transcript_exon_variant 0.18
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.21
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.26
rrl 1473467 n.-191A>G upstream_gene_variant 0.18
embB 4247824 c.1311C>A synonymous_variant 0.17