TB-Profiler result

Run: SRR5485589
Summary

Run ID: SRR5485589

Sample name:

Date: 18-08-2022 08:23:49

Number of reads: 97129

Percentage reads mapped: 99.06

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 0.95 streptomycin
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7618 p.Arg106His missense_variant 0.18
gyrA 7668 p.Pro123Ser missense_variant 0.17
rpoB 761218 p.Pro471Gln missense_variant 0.21
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.33
rrs 1473370 n.1525T>C non_coding_transcript_exon_variant 0.14
katG 2155200 c.912T>C synonymous_variant 1.0
pncA 2289051 p.Tyr64Ser missense_variant 0.15