Run ID: SRR5485594
Sample name:
Date: 18-08-2022 08:23:27
Number of reads: 86616
Percentage reads mapped: 98.91
Strain:
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761139 | p.His445Asp | missense_variant | 1.0 | rifampicin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
pncA | 2288957 | p.Tyr95* | stop_gained | 0.77 | pyrazinamide |
embB | 4247429 | p.Met306Val | missense_variant | 1.0 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.14 |
gyrB | 6641 | p.Lys468Glu | missense_variant | 0.14 |
gyrA | 7637 | c.336C>A | synonymous_variant | 0.17 |
gyrA | 7638 | p.Gln113* | stop_gained | 0.17 |
rpoB | 761228 | p.Tyr474* | stop_gained | 0.2 |
rrs | 1472314 | n.471delT | non_coding_transcript_exon_variant | 0.2 |
rrs | 1472493 | n.648T>G | non_coding_transcript_exon_variant | 0.33 |
pncA | 2288924 | p.Phe106Leu | missense_variant | 0.23 |
pncA | 2289052 | p.Tyr64His | missense_variant | 0.15 |
embB | 4247401 | c.888T>C | synonymous_variant | 0.15 |