Run ID: SRR5485595
Sample name:
Date: 18-08-2022 08:23:27
Number of reads: 82395
Percentage reads mapped: 99.15
Strain:
Drug-resistance: RR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761101 | p.Gln432Arg | missense_variant | 1.0 | rifampicin |
rpsL | 781822 | p.Lys88Arg | missense_variant | 1.0 | streptomycin |
rrs | 1472723 | n.878G>A | non_coding_transcript_exon_variant | 0.14 | streptomycin |
embB | 4247431 | p.Met306Ile | missense_variant | 0.15 | ethambutol |
embB | 4247465 | p.Asn318His | missense_variant | 0.2 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7623 | p.Pro108Ser | missense_variant | 0.2 |
gyrA | 7647 | p.Phe116Leu | missense_variant | 0.2 |
rrs | 1472493 | n.648T>G | non_coding_transcript_exon_variant | 0.28 |
rrs | 1473208 | n.1363G>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473216 | n.1371C>G | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473245 | n.1400C>T | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473262 | n.1417T>C | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473266 | n.1421A>G | non_coding_transcript_exon_variant | 0.18 |
rrs | 1473300 | n.1455C>T | non_coding_transcript_exon_variant | 0.18 |
rrl | 1473393 | n.-265A>G | upstream_gene_variant | 0.14 |
rrl | 1473412 | n.-245delG | upstream_gene_variant | 0.14 |
pncA | 2289160 | p.Ala28Thr | missense_variant | 1.0 |
pncA | 2289168 | p.Ala25Asp | missense_variant | 0.18 |
embB | 4247352 | p.Asp280Ala | missense_variant | 0.15 |
embB | 4247448 | p.His312Pro | missense_variant | 0.23 |
embB | 4247503 | p.Phe330Leu | missense_variant | 1.0 |