TB-Profiler result

Run: SRR5485597
Summary

Run ID: SRR5485597

Sample name:

Date: 18-08-2022 08:23:15

Number of reads: 92885

Percentage reads mapped: 99.01

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
embB 4247429 p.Met306Val missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761221 p.Ser472Leu missense_variant 0.17
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.23
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.15
embB 4247350 c.837C>T synonymous_variant 0.15
embB 4247512 p.Tyr333* stop_gained 0.15